A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study
Using single-cell genomic datasets of ASS PBMCs, we revealed a distinctive profile in the immune system of individuals with ASS, compared to that with MDA5<sup>+</sup> DM or healthy controls.
Authors
- Tong Yang (ORCID: https://orcid.org/0000-0003-4438-2568)
- Yingai Wang
- Jiayu Ding (ORCID: https://orcid.org/0009-0002-0276-7582)
- Gaoya Wang
- Yong Xu (ORCID: https://orcid.org/0000-0002-4908-1572)
- Zhiqin Wang (ORCID: https://orcid.org/0000-0002-1708-7689)
- Zhigang Cai (ORCID: https://orcid.org/0009-0003-2416-9951)
- Wei Wei (ORCID: https://orcid.org/0000-0002-4386-8577)
- Na Zhang (ORCID: https://orcid.org/0000-0001-9534-0320)
- Mei Zhang (ORCID: https://orcid.org/0000-0002-1543-4253)
- Ming Chen (ORCID: https://orcid.org/0000-0002-4178-9314)
- Jian Hao (ORCID: https://orcid.org/0000-0001-7202-0199)
- Jun Du
- Yanmei Li (ORCID: https://orcid.org/0009-0001-1232-7954)
- Xinlei Liu (ORCID: https://orcid.org/0000-0001-7552-1597)
- Guangxin Zhang (ORCID: https://orcid.org/0000-0001-9152-8270)
- Feng Han (ORCID: https://orcid.org/0000-0002-0274-9272)
- Xiuhua Wu
- Wenwen Sun (ORCID: https://orcid.org/0000-0003-2657-2536)
- Jing Xu (ORCID: https://orcid.org/0000-0001-6877-3577)
Institutions
- Tianjin Medical University General Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3389/fimmu.2024.1436114
- Citations
- 4
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Tianjin Medical University
- National Institutes of Health