Cardiovascular disease risk in patients with elevated LDL-C levels: FH vs. non-FH
FH mutation did not increase the rate of CAD in individuals with an MLDL-C level ≥4.0 mmol/L. However, among CAD patients (MLDL-C level ≥4.0 mmol/L) with almost normal renal function (≥87.4 ml/min/1.73 m<sup>2</sup>), the probability of enduring TVD in those with FH mutations in 3 major genes was 3.00 times greater than that in those without FH mutations.
Authors
- Anni Yang
- Haomin Huang
- Ganwei Shi (ORCID: https://orcid.org/0000-0001-5242-0187)
- Luya Wang (ORCID: https://orcid.org/0000-0001-6092-0720)
- Lamei Li (ORCID: https://orcid.org/0000-0003-4782-8094)
- Gaojun Cai (ORCID: https://orcid.org/0000-0003-4250-180X)
- Feng Li (ORCID: https://orcid.org/0000-0002-6172-1325)
- Tao Chen (ORCID: https://orcid.org/0000-0003-2796-6748)
Institutions
- Jiangsu University (CN)
- Xuzhou Medical College (CN)
- Capital Medical University (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Beijing Anzhen Hospital (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3389/fcvm.2024.1434392
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.57