Neuroleptic malignant syndrome in Huntington disease

NMS in HD patients is seldom described. This could be due to an underestimation of this condition. There are no available objective NMS diagnostic criteria at present, and the existence of atypical forms of NMS further complicates diagnosis. Advanced disease stage, rigid-akinetic phenotype, abrupt therapy changes, polytherapy, and dehydration are key risk factors, most of which are preventable through awareness and caution in managing medications in the HD population.

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Publication Details

Journal
European Journal of Neurology
Published
2024-10-23
DOI
https://doi.org/10.1111/ene.16442
Citations
3
Primary Topic
Electroconvulsive Therapy Studies
Type
article
Field-Weighted Citation Impact
1.16
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article

Neuroleptic malignant syndrome in Huntington disease

Paola Zinzi, Anna Rita Bentivoglio, Marcella Solito, Paolo Calabresi et al.
3 citations
European Journal of Neurology
Electroconvulsive Therapy Studies
1.16
article

Neuroleptic malignant syndrome in Huntington disease

Paola Zinzi, Anna Rita Bentivoglio, Marcella Solito, Paolo Calabresi, Martina Petracca, Beatrice Ravera, Antonio Funcis
article en
3 citations

Abstract

NMS in HD patients is seldom described. This could be due to an underestimation of this condition. There are no available objective NMS diagnostic criteria at present, and the existence of atypical forms of NMS further complicates diagnosis. Advanced disease stage, rigid-akinetic phenotype, abrupt therapy changes, polytherapy, and dehydration are key risk factors, most of which are preventable through awareness and caution in managing medications in the HD population.

European Journal of NeurologyVol. 31(12)
Università Cattolica del Sacro Cuore (IT), Agostino Gemelli University Polyclinic (IT)
Good health and well-being
Openalex Percentile: Top 20%
Electroconvulsive Therapy Studies
1.16
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