Antiproliferative Activity of Cephalotaxus Esters: Overcoming Chemoresistance
Taken together, our results confirm that HHT is a substrate for MDR1. It opens the door to a new opportunity to clinically evaluate HHT and its derivatives for the treatment of AML and other cancers.
Authors
- Paul Calder
- Hakim Djaballah (ORCID: https://orcid.org/0000-0002-6039-0181)
- Vladimir Yong‐Gonzalez
- David Shum (ORCID: https://orcid.org/0000-0002-2349-5670)
- Mark G. Frattini
- Constantin Radu
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Institut Pasteur Korea (KR)
- Cellectis (United States) (US)
- Molecular Devices
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2024-10-24
- DOI
- https://doi.org/10.2174/0113862073322175240823104921
- Citations
- 1
- Primary Topic
- Biological Activity of Diterpenoids and Biflavonoids
- Type
- article
- Field-Weighted Citation Impact
- 0.23