Unveiling the Therapeutic Potential of Small Molecule of SVAK-12: A Comprehensive In Silico, In Vitro, and In Vivo Studies on its Neuroprotective Effects and Molecular Interactions in Parkinson's Disease
Overall, the study suggests that SVAK-12's neuro-biocompatibility, ability to reduce free radicals, and enhanced neurotrophic factors make it a promising candidate as a neuroprotective drug.
Authors
- Shima Tavakol (ORCID: https://orcid.org/0000-0002-8531-7650)
- Seyed Abdolhamid Angaji (ORCID: https://orcid.org/0000-0001-9560-5157)
- Mahmood Barati (ORCID: https://orcid.org/0000-0002-9663-9313)
- Sara Simorgh (ORCID: https://orcid.org/0000-0001-6246-9531)
- Ali Shahbazi (ORCID: https://orcid.org/0000-0001-5222-4792)
- Mojgan Yazdanpanah
- Fereshteh Azedi (ORCID: https://orcid.org/0000-0001-9776-7686)
- Mobina Amiri
- Shayesteh Kokabi
- Niloofar Alahdad
Institutions
- Iran University of Medical Sciences (IR)
- Kharazmi University (IR)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2024-10-24
- DOI
- https://doi.org/10.2174/0109298673329597241006053718
- Citations
- 1
- Primary Topic
- Nuclear Receptors and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.27