Critical role for platelet Ral GTPases in regulating venous thrombosis in mice
We identify platelet Rals as novel, potentially critical regulators of venous thrombus stability through their ability to regulate neutrophil NET formation via platelet P-selectin.
Authors
- Jordan Vautrinot (ORCID: https://orcid.org/0000-0001-7957-360X)
- Alastair W. Poole (ORCID: https://orcid.org/0000-0002-0868-297X)
- Alexander Brill (ORCID: https://orcid.org/0000-0002-4558-0390)
- Tony G. Walsh (ORCID: https://orcid.org/0000-0002-0403-3999)
- Christopher Williams (ORCID: https://orcid.org/0000-0001-5806-9842)
- Borko Amulic (ORCID: https://orcid.org/0000-0002-8518-8393)
- Yong Li (ORCID: https://orcid.org/0000-0001-6266-8717)
- Jonathan Alan Furniss
Institutions
- University of Bristol (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1016/j.jtha.2024.10.010
- Citations
- 8
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Wellcome Trust
- British Heart Foundation
- University of Bristol
- Medical Research Council