The Influence of Pelvic Bone Dose-volume Parameters on Bone Marrow Suppression During Radiation Therapy in Patients With Stage I to III Rectal Cancer Based on Real-world Data
Among patients with rectal cancer stage I to III disease who received neo-RT or cur-RT, female patients with higher IBM-Dmean, IBM-V15, and IBM-V40 were more likely to experience grade 2+ leukopenia, and oxaliplatin-containing concurrent ChT regimens were identified as a potential factor for increasing the incidence of grade 2+ thrombocytopenia.
Authors
- L. M. Zhuo
- Shaoqing Niu (ORCID: https://orcid.org/0000-0003-1070-0601)
- Botian Huang
- Yong Bao (ORCID: https://orcid.org/0000-0002-2792-5957)
- Fang Peng (ORCID: https://orcid.org/0000-0001-8877-3283)
- Xiaowu Deng (ORCID: https://orcid.org/0000-0003-2923-1251)
- Zhuangzhuang Yang
- Junwei Lv (ORCID: https://orcid.org/0000-0001-7278-6864)
- Jianqi Xiong
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- First Hospital of China Medical University (CN)
- Sun Yat-sen University Cancer Center (CN)
- China Medical University (CN)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1016/j.adro.2024.101662
- Citations
- 3
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Natural Science Foundation of Guangdong Province
- Guangdong Medical Research Foundation