Metabolite <scp>T<sub>2</sub></scp> relaxation times decrease across the adult lifespan in a large multi‐site cohort
These findings underscore the importance of considering metabolite T<sub>2</sub> differences with aging in MRS quantification. We suggest that future 3T work utilize the equations presented here to estimate age-specific T<sub>2</sub> values instead of relying on uniform default values.
Authors
- Kathleen E. Hupfeld (ORCID: https://orcid.org/0000-0001-5086-4841)
- Gizeaddis Lamesgin Simegn (ORCID: https://orcid.org/0000-0003-1333-4555)
- Helge J. Zöllner (ORCID: https://orcid.org/0000-0002-7148-292X)
- Aaron T. Gudmundson (ORCID: https://orcid.org/0000-0001-5104-0959)
- Georg Oeltzschner (ORCID: https://orcid.org/0000-0003-3083-9811)
- Dunja Simičić (ORCID: https://orcid.org/0000-0002-6600-2696)
- Richard A.E. Edden (ORCID: https://orcid.org/0000-0002-0671-7374)
- Emily Carter
- Steve C. N. Hui (ORCID: https://orcid.org/0000-0002-1523-4040)
- Saipavitra Murali‐Manohar (ORCID: https://orcid.org/0000-0002-4978-0736)
- Eric C. Porges (ORCID: https://orcid.org/0000-0003-3885-5859)
- Yulu Song (ORCID: https://orcid.org/0000-0002-4416-7959)
- Christopher W. Davies‐Jenkins (ORCID: https://orcid.org/0000-0002-6015-762X)
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
Institutions
- Kennedy Krieger Institute (US)
- Children's National (US)
- Johns Hopkins University (US)
- George Washington University (US)
- University of Florida Health (US)
- University of Florida (US)
- University of Baltimore (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1002/mrm.30340
- Citations
- 6
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.43
Funders
- National Institute on Aging
- National Institute of Biomedical Imaging and Bioengineering