Clinical characteristics and prognosis of interstitial lung disease in systemic juvenile idiopathic arthritis: a two-center retrospective observational cohort study
Patients with SJIA-ILD exhibited heightened inflammation, increased hip joint and cervical spine involvement, and were more susceptible to developing lymphopenia and MAS, suggesting a relatively poor prognosis. They required a prolonged time to control inflammation and more aggressive treatment strategies to achieve inactive status. The unsatisfactory rate of complete remission highlighted an urgent need for focused clinical strategies.
Authors
- Lingzhi Qiu
- Xiaohua Ye (ORCID: https://orcid.org/0009-0002-8590-9880)
- Yaoyao Shangguan (ORCID: https://orcid.org/0009-0004-0498-2045)
- Wenting Zhan
- Haiguo Yu (ORCID: https://orcid.org/0000-0001-8255-9390)
- Wen Jie Zheng (ORCID: https://orcid.org/0000-0002-1768-4432)
- Kangkang Yang (ORCID: https://orcid.org/0009-0000-2981-9544)
- Jinxiang Yang (ORCID: https://orcid.org/0009-0007-3733-1996)
Institutions
- Shanghai Jiao Tong University (CN)
- Wenzhou Medical University (CN)
- XinHua Hospital (CN)
- Nanjing Children's Hospital (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s12969-024-01028-5
- Citations
- 5
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 2.27
Funders
- Basic Research Project of Wenzhou City
- Medical Science and Technology Project of Zhejiang Province
- Natural Science Foundation of Zhejiang Province