Phenotypic Characterization of Intensive Care Patients With Infections: A Pilot Study of Host and Pathogen-Based Cluster Analysis

The cluster analysis approach provided valuable insights into the complex interplay between bacterial virulence, infection site, and patient outcomes in critical care medicine. Patients infected with bacteraemia by Gram-positive bacteria (cluster 2) or Enterobacteriaceae (Cluster 5) and fungal isolation in respiratory samples (Cluster 3) should prompt more aggressive clinical interventions, as these patients are more prone to die in the hospital.

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Publication Details

Journal
Cureus
Published
2024-10-24
DOI
https://doi.org/10.7759/cureus.72255
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Phenotypic Characterization of Intensive Care Patients With Infections: A Pilot Study of Host and Pathogen-Based Cluster Analysis

João Gonçalves-Pereira, Ana Rita Fernandes, Tânia F Mendes, André Oliveira
Cureus
Sepsis Diagnosis and Treatment
article

Phenotypic Characterization of Intensive Care Patients With Infections: A Pilot Study of Host and Pathogen-Based Cluster Analysis

João Gonçalves-Pereira, Ana Rita Fernandes, Tânia F Mendes, André Oliveira
article en

Abstract

The cluster analysis approach provided valuable insights into the complex interplay between bacterial virulence, infection site, and patient outcomes in critical care medicine. Patients infected with bacteraemia by Gram-positive bacteria (cluster 2) or Enterobacteriaceae (Cluster 5) and fungal isolation in respiratory samples (Cluster 3) should prompt more aggressive clinical interventions, as these patients are more prone to die in the hospital.

CureusVol. 16(10)
University of Lisbon (PT), Hospital Vila Franca de Xira (PT)
Openalex Percentile: Top 72%
Sepsis Diagnosis and Treatment
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