Molecular Alterations in Paired Epithelial Ovarian Tumors in Patients Treated with Neoadjuvant Chemotherapy
This study provides insights into the effect of NACT on the tumor molecular landscape. While BRCA1/2 and HRD status remained stable, an increase in TIL proportion and changes in the mutational profiles were observed post-treatment.
Authors
- Georgios Tsaousis (ORCID: https://orcid.org/0000-0002-8975-8779)
- Eirini Papadopoulou (ORCID: https://orcid.org/0000-0001-5519-5325)
- Adamantia Nikolaidi (ORCID: https://orcid.org/0000-0003-2057-9585)
- Sofia Karageorgopoulou (ORCID: https://orcid.org/0000-0002-5628-3121)
- Dimitrios Haidopoulos (ORCID: https://orcid.org/0000-0001-9366-9691)
- Sofia Stamatopoulou
- ANNA C. GOUSSIA (ORCID: https://orcid.org/0000-0002-4134-6177)
- Michalis Liontos (ORCID: https://orcid.org/0000-0001-7192-4575)
- Christos Papadimitriou (ORCID: https://orcid.org/0000-0001-8084-0445)
- Athina Christopoulou (ORCID: https://orcid.org/0000-0002-9402-2045)
- Eleftheria Tsolaki (ORCID: https://orcid.org/0000-0003-1463-1754)
- Ioannis Binas
- Anna Koumarianou (ORCID: https://orcid.org/0000-0002-4159-2511)
- Elena Fountzilas (ORCID: https://orcid.org/0000-0002-4884-2544)
- Helen J Gogas (ORCID: https://orcid.org/0000-0002-0451-2885)
- Kalliroi Goula
- Amanda Psyrri
Institutions
- National and Kapodistrian University of Athens (GR)
- European University Cyprus (CY)
- Aristotle University of Thessaloniki (GR)
- General University Hospital of Patras (GR)
- Alexandra Hospital (GR)
- General Hospital of Drama (GR)
- Mitera Hospital (GR)
- Athens Medical Center (GR)
- University Hospital of Ioannina (GR)
- IASO General Hospital (GR)
- Metropolitan Hospital (GR)
Publication Details
- Journal
- Cancers
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3390/cancers16213580
- Citations
- 2
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.07