Exploring the longitudinal expression dynamics of midguts in adult female Amblyomma americanum ticks

Our findings provide a detailed temporal resolution of numerous metabolic pathways in the midgut of A. americanum adult females throughout the feeding process, highlighting the dynamic transcriptional regulation of the tick's midgut as feeding progresses. Furthermore, we identified conserved transcripts across three different tick species that exhibit similar expression patterns. This knowledge not only enhances our understanding of the physiological processes within the tick midgut but also opens up potential avenues for developing control methods that target multiple tick species.

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Publication Details

Journal
BMC Genomics
Published
2024-10-24
DOI
https://doi.org/10.1186/s12864-024-10905-y
Citations
5
Primary Topic
Vector-borne infectious diseases
Type
article
Field-Weighted Citation Impact
2.58

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article

Exploring the longitudinal expression dynamics of midguts in adult female Amblyomma americanum ticks

Lucas Christian de Sousa‐Paula, José M. C. Ribeiro, Lucas Tirloni, Stephen Lu
5 citations
BMC Genomics
Vector-borne infectious diseases
2.58
article

Exploring the longitudinal expression dynamics of midguts in adult female Amblyomma americanum ticks

Lucas Christian de Sousa‐Paula, José M. C. Ribeiro, Lucas Tirloni, Stephen Lu
article en
5 citations

Abstract

Our findings provide a detailed temporal resolution of numerous metabolic pathways in the midgut of A. americanum adult females throughout the feeding process, highlighting the dynamic transcriptional regulation of the tick's midgut as feeding progresses. Furthermore, we identified conserved transcripts across three different tick species that exhibit similar expression patterns. This knowledge not only enhances our understanding of the physiological processes within the tick midgut but also opens up potential avenues for developing control methods that target multiple tick species.

BMC GenomicsVol. 25(1)
Vector (United States) (US), National Institute of Allergy and Infectious Diseases (US)
National Institutes of Health, National Institute of Allergy and Infectious Diseases
Openalex Percentile: Top 10%
Vector-borne infectious diseases
2.58
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