Exploring the longitudinal expression dynamics of midguts in adult female Amblyomma americanum ticks
Our findings provide a detailed temporal resolution of numerous metabolic pathways in the midgut of A. americanum adult females throughout the feeding process, highlighting the dynamic transcriptional regulation of the tick's midgut as feeding progresses. Furthermore, we identified conserved transcripts across three different tick species that exhibit similar expression patterns. This knowledge not only enhances our understanding of the physiological processes within the tick midgut but also opens up potential avenues for developing control methods that target multiple tick species.
Authors
- Lucas Christian de Sousa‐Paula (ORCID: https://orcid.org/0000-0002-3379-1609)
- José M. C. Ribeiro (ORCID: https://orcid.org/0000-0002-9107-0818)
- Lucas Tirloni (ORCID: https://orcid.org/0000-0003-4582-7100)
- Stephen Lu (ORCID: https://orcid.org/0000-0001-6893-3710)
Institutions
- Vector (United States) (US)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s12864-024-10905-y
- Citations
- 5
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases