Effects of Acupuncture and Tuina Combined with Rehabilitation Therapy on Oxidative Stress Response and Motor Function in Stroke Hemiplegia Patients

Objective: To explore the effects of acupuncture and tuina combined with rehabilitation therapy on oxidative stress response and motor function in stroke hemiplegia patients. Methods: Sixty stroke hemiplegia patients were randomly divided into observation and control groups, with 30 cases each. The control group received conventional rehabilitation therapy, while the observation group also underwent acupuncture and tuina. After 8 weeks of treatment, oxidative stress indicators [malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px)], neurological deficit scores (NIHSS), Fugl-Meyer motor function scores (FMA), and activities of daily living (Barthel Index) were compared between the two groups. Results: Before treatment, there were no significant differences in MDA, NIHSS scores, FMA scores, and Barthel Index between the two groups (P > 0.05). After 8 weeks, the observation group had lower MDA and NIHSS scores, but higher SOD, GSH-Px, FMA scores, and Barthel Index compared to the control group, with statistically significant differences (P < 0.05). Conclusion: Acupuncture and tuina combined with rehabilitation therapy can effectively improve oxidative stress levels, promote neurological recovery, enhance motor function, and improve daily living activities in stroke hemiplegia patients. This combined therapy is recommended for clinical application.