Is castration leading to biological aging in dogs? Assessment of lipid peroxidation, inflammation, telomere length, mitochondrial DNA copy number, and expression of telomerase and age-related genes
Castration appears to have a protective effect against biological aging in dogs, as evidenced by lower lipid peroxidation, inflammation, and age-related changes in telomere length, mtDNA copy number, and gene expression.
Authors
- Reza Jalali
- Hossein Hassanpour (ORCID: https://orcid.org/0000-0002-9980-8100)
- Moosa Javdani (ORCID: https://orcid.org/0000-0003-0975-2295)
- Marzieh Mojtahed
- Zahra Changaniyan-Khorasgani
- Elnaz Rezazadeh
Institutions
- Shahed University (IR)
- Shahrekord University (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s12917-024-04337-9
- Citations
- 4
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Shahrekord University