Age, sex, and cell type-resolved hypothalamic gene expression across the pubertal transition in mice
Together, by incorporating multiple biological timepoints and using sex as a variable, we identified gene and cell-type changes that may participate in orchestrating the pubertal transition and provided a resource for future studies of postnatal hypothalamic gene regulation.
Authors
- Mark R. Palmert (ORCID: https://orcid.org/0000-0002-4096-0685)
- Huayun Hou (ORCID: https://orcid.org/0000-0003-3971-1427)
- Cadia Chan (ORCID: https://orcid.org/0000-0002-4810-8366)
- Christina Corre (ORCID: https://orcid.org/0000-0002-7631-6066)
- Michael D. Wilson (ORCID: https://orcid.org/0000-0002-4015-3066)
- Kyoko E. Yuki (ORCID: https://orcid.org/0000-0003-0726-3914)
- Matthew B. Hudson (ORCID: https://orcid.org/0000-0003-0998-0191)
- Liis Uusküla-Reimand (ORCID: https://orcid.org/0000-0002-5322-5524)
- Wendy W. Y. Choi (ORCID: https://orcid.org/0000-0003-0794-3215)
- Anna Roy
- Dustin Sokolowski (ORCID: https://orcid.org/0000-0002-4057-3183)
- Mariela Faykoo-Martinez (ORCID: https://orcid.org/0000-0002-8885-657X)
- Anna Goldenberg (ORCID: https://orcid.org/0000-0002-2416-833X)
Institutions
- Canadian Institute for Advanced Research (CA)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Occupational Cancer Research Centre (CA)
- Vector Institute (CA)
- SickKids Foundation (CA)
- The Wilson Centre (CA)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s13293-024-00661-9
- Citations
- 4
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Genome Canada
- Ontario Genomics
- Canada Research Chairs
- Hospital for Sick Children
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada