Evidence of Clinical and Laboratory Correlation of Itraconazole Resistance in Sporothrix brasiliensis Infection: Case Report
Sporotrichosis is a subcutaneous infection caused by fungi from the genus <i>Sporothrix</i>, among which <i>Sporothrix brasiliensis</i> displays high virulence and transmissibility. So far, classical antifungal agents have been efficient against <i>S. brasiliensis</i>, but here we describe the first case of therapeutic failure and a high minimum inhibitory concentration (MIC) in relation to itraconazole.
Authors
- Tânia Sueli de Andrade (ORCID: https://orcid.org/0000-0002-4547-6462)
- Ana Paula Carvalho Reis (ORCID: https://orcid.org/0000-0001-8962-2532)
- Giovanna Azevedo Celestrino (ORCID: https://orcid.org/0000-0002-2990-1537)
- Maria Glória Teixeira Sousa (ORCID: https://orcid.org/0000-0003-4157-1945)
- Eduardo José Ferreira Santos (ORCID: https://orcid.org/0000-0003-0557-2377)
- Dhulyane de Sousa Mendes
- John Verrinder Veasey (ORCID: https://orcid.org/0000-0002-4256-5734)
- Lucas Xavier Bonfietti (ORCID: https://orcid.org/0000-0002-2554-1853)
- Gil Benard (ORCID: https://orcid.org/0000-0002-5469-3602)
- Camila Estacia Silva
Institutions
- Instituto Adolfo Lutz (BR)
- Faculdade de Ciências Médicas da Santa Casa de São Paulo (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Microorganisms
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3390/microorganisms12112132
- Citations
- 4
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo