Investigating the Unexpected Effect of Bulkheads in a Dementia Model of Mice Through Molecular Analysis of the Hippocampus
Prolonged physical isolation, even with visual contact, can adversely affect cognitive function and hippocampal structure in dementia models. Changes in gene expression indicate that neurotransmitter imbalances and neuroinflammatory responses may contribute to these effects. These findings emphasize the need to develop new infection-prevention measures for patients with dementia during the COVID-19 pandemic.
Authors
- Nobuo Kato (ORCID: https://orcid.org/0000-0001-7584-2542)
- Munenori Ono (ORCID: https://orcid.org/0000-0001-9421-7021)
- Tadashi Ueda (ORCID: https://orcid.org/0000-0002-4555-2445)
- Tsugiyasu Kanda (ORCID: https://orcid.org/0000-0002-9388-5711)
- Daisuke Sakamoto (ORCID: https://orcid.org/0000-0002-2219-4198)
- Yuji Kasamaki (ORCID: https://orcid.org/0000-0003-3515-6331)
- Tetsuhiro Horie (ORCID: https://orcid.org/0000-0002-2095-9425)
- Yasuo Yoshitomi (ORCID: https://orcid.org/0000-0002-9935-5324)
- Yasuhito Ishigaki (ORCID: https://orcid.org/0000-0003-1012-8430)
- Takuya Sakamoto (ORCID: https://orcid.org/0000-0003-2519-4510)
Institutions
- Kanazawa Medical University (JP)
- Kanazawa Medical University Hospital (JP)
Publication Details
- Journal
- Cureus
- Published
- 2024-10-24
- DOI
- https://doi.org/10.7759/cureus.72272
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kanazawa Medical University