Identification of novel sub-phenotypes of severe ARDS requiring ECMO using latent class analysis
The three sub-phenotypes showed different mortality rates and different relationships between higher PEEP settings in the early phase of V-V ECMO and patient outcomes. Our data suggest that we may need to change our management approach to patients with severe ARDS during V-V ECMO according to their clinical sub-phenotype.
Authors
- Naofumi Bunya (ORCID: https://orcid.org/0000-0003-3605-402X)
- Giacomo Bellani (ORCID: https://orcid.org/0000-0002-3089-205X)
- Junichi Maruyama (ORCID: https://orcid.org/0000-0002-3665-2700)
- Mamoru Masuda
- Kazuki Matsumura (ORCID: https://orcid.org/0000-0001-9367-1636)
- Kenji Fujizuka (ORCID: https://orcid.org/0000-0003-2732-2774)
- Yoshihiro Hagiwara (ORCID: https://orcid.org/0000-0002-2992-2178)
- Shinichiro Ohshimo (ORCID: https://orcid.org/0000-0003-1119-3322)
- Keibun Liu (ORCID: https://orcid.org/0000-0002-6867-1420)
- Michihito Kyo (ORCID: https://orcid.org/0000-0002-2559-6440)
- Ryuichi Nakayama (ORCID: https://orcid.org/0000-0002-3272-7680)
- Takayuki Ogura (ORCID: https://orcid.org/0000-0002-2525-4985)
- Wataru Fukumoto (ORCID: https://orcid.org/0000-0001-7645-8446)
- Nobuaki Shime (ORCID: https://orcid.org/0000-0002-9113-6151)
- Mitsuaki Nishikimi (ORCID: https://orcid.org/0000-0003-2342-7245)
- Junki Ishii (ORCID: https://orcid.org/0000-0001-9661-3693)
- Kunihiko Takahashi (ORCID: https://orcid.org/0000-0003-2387-7772)
- Mitsunobu Nakamura (ORCID: https://orcid.org/0000-0001-7400-5531)
- Kazuo Awai (ORCID: https://orcid.org/0000-0002-5039-2546)
- Jun Hamaguchi (ORCID: https://orcid.org/0009-0009-3410-8101)
- Keiki Shimizu
- Tatsuhiko Anzai
Institutions
- Hiroshima University (JP)
- Tokyo Medical and Dental University (JP)
- Sapporo Medical University (JP)
- The University of Queensland (AU)
- University of Trento (IT)
- Ospedale Santa Chiara (IT)
- Fukuoka University Hospital (JP)
- Maebashi Red Cross Hospital (JP)
- Saiseikai Utsunomiya hospital (JP)
- Prince Charles Hospital (AU)
- Tokyo Metropolitan Tama Medical Center (JP)
Publication Details
- Journal
- Critical Care
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s13054-024-05143-3
- Citations
- 13
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- Japan Agency for Medical Research and Development
- Fukuoka University
- Japan Society for the Promotion of Science