Distinct Immunophenotypes in the DNA Index-Based Stratification of Pediatric B-Cell Acute Lymphoblastic Leukemia
This study found that hypoploid B-ALL patients have distinct characteristics, such as lower S-phase cell percentages and specific immunophenotypic profiles, including higher HLA-DR expression and CD34/CD22 co-expression. These differences across DNA index-based prognostic categories warrant further research to explore their potential prognostic significance.
Authors
- María Isabel Mendoza‐Ramos
- Carlos Leonardo Duarte-Martínez
- Sandra Olivas-Quintero (ORCID: https://orcid.org/0000-0002-7517-6460)
- Adolfo Rene Méndez-Cruz
- M. Hernández (ORCID: https://orcid.org/0000-0002-6932-5853)
- Julia Reyes‐Reali
- Wilfrido David Tapia-Sánchez
- Glustein Pozo‐Molina (ORCID: https://orcid.org/0000-0002-4675-4081)
- J. Rafael Jiménez-Flores (ORCID: https://orcid.org/0000-0002-8004-1253)
- Alberto Ponciano-Gómez (ORCID: https://orcid.org/0000-0002-1801-6575)
- Myriam Campos-Aguilar
- Alberto Daniel Saucedo–Campos (ORCID: https://orcid.org/0000-0002-6707-5774)
- Elías Piedra‐Ibarra (ORCID: https://orcid.org/0000-0002-7030-4769)
- Victor Hugo Rosales-García
- Leopoldo Santos‐Argumedo (ORCID: https://orcid.org/0000-0002-4772-0713)
- Almarosa Ruiz-Ochoa
Institutions
- Universidad Autónoma de Tlaxcala (MX)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Cancers
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3390/cancers16213585
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México