Association of cumulative oxygen and carbon dioxide levels with neurologic outcome after pediatric cardiac arrest resuscitation: A multicenter cohort study
Cumulative PaO<sub>2</sub> and PaCO<sub>2</sub> exposure in the first 24 h post-return of circulation was not associated with survival with favorable neurologic outcome. Pediatric AHA post-cardiac arrest care guideline normoxia and normocapnia goals were often not met. Larger cohort studies are necessary to improve the accuracy of cumulative exposure calculations, assess the long-term effects of PaO<sub>2</sub> and PaCO<sub>2</sub> exposure, and explore the influence of other post-cardiac arrest care therapeutic strategies.
Authors
- Andrea Christoff
- Kari Wellnitz (ORCID: https://orcid.org/0000-0001-9451-8879)
- Rogier C.J. de Jonge (ORCID: https://orcid.org/0000-0003-0595-1983)
- Jimena del Castillo (ORCID: https://orcid.org/0000-0002-0702-1520)
- Vinay Nadkarni (ORCID: https://orcid.org/0000-0002-3794-5599)
- Dana Niles
- Matthijs de Hoog (ORCID: https://orcid.org/0000-0002-1259-581X)
- Sangmo Je (ORCID: https://orcid.org/0000-0003-0818-2286)
- Oliver Tegg
- M. Albrecht (ORCID: https://orcid.org/0000-0002-4305-6288)
- Corinne Buysse
Institutions
- University of Iowa (US)
- Children's Hospital of Philadelphia (US)
- Children's Hospital at Westmead (AU)
- Hospital General Universitario Gregorio Marañón (ES)
- Erasmus MC - Sophia Children’s Hospital (NL)
- University of Iowa Health Care (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1016/j.resplu.2024.100804
- Citations
- 6
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 4.15