Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response

Our findings suggest that IIQs may be promising new agents for a subset of EWS patients.

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Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2024-10-24
DOI
https://doi.org/10.3389/fcell.2024.1462840
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response

Deborah B. Householder, Melanie B. Gordon, Christine M. Heske, Kristine Johnson et al.
Frontiers in Cell and Developmental Biology
Sarcoma Diagnosis and Treatment
article

Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response

Deborah B. Householder, Melanie B. Gordon, Christine M. Heske, Kristine Johnson, Cody J. Peer, Fathi Elloumi, Ludmila Szabova, S. Jorgensen, Ryan D. Roberts, Sudhir Varma, Unsun Lee, Sophia Varriano, Victor J. Collins, Yves Pommier, Shyam K. Sharan, Zoë Weaver Ohler, Laura Bassel, Lucy Lu, William D. Figg, Ariana E. Nelson
article en

Abstract

Our findings suggest that IIQs may be promising new agents for a subset of EWS patients.

Frontiers in Cell and Developmental BiologyVol. 12
National Institutes of Health (US), Nationwide Children's Hospital (US), Frederick National Laboratory for Cancer Research (US), National Cancer Institute (US), Center for Cancer Research (US)
Cancer Research Institute, St. Jude Children's Research Hospital, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 66%
Sarcoma Diagnosis and Treatment
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Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response — Deborah B. Householder, Melanie B. Gordon, et al. · Frontiers in Cell and Developmental Biology (2024) | TGRS Research Map | TGRS