COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery

There is a need for innovation to improve the surgical approach to vaginal apical suspension. Despite controversies with mesh, it has been shown to be safe when used appropriately and to have higher durability when compared with sutures. As well, the importance of restoring anatomy and tension-free surgical approach in pelvic reconstructive surgery has led to better long-term outcomes and fewer side effects. These principles have been applied when developing the novel BSSVF-M technique. Anticipated challenges of this trial include recruitment, compliance problems and loss to follow up However, the robust methodology will provide evidence on the best surgical approach to correct POP, a common condition among aging women.

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Publication Details

Journal
PLoS ONE
Published
2024-10-24
DOI
https://doi.org/10.1371/journal.pone.0308926
Citations
5
Primary Topic
Pelvic floor disorders treatments
Type
article
Field-Weighted Citation Impact
2.35

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article

COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery

Ola Malabarey, Maryse Larouche, Wei Zhang, Lori A. Brotto et al.
5 citations
PLoS ONE
Pelvic floor disorders treatments
2.35
article

COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery

Ola Malabarey, Maryse Larouche, Wei Zhang, Lori A. Brotto, Lina Roa, Momoe Hyakutake, Nicole Koenig, Roxana Geoffrion, Erin A. Brennand, Joel Singer, Terry Lee
article en
5 citations

Abstract

There is a need for innovation to improve the surgical approach to vaginal apical suspension. Despite controversies with mesh, it has been shown to be safe when used appropriately and to have higher durability when compared with sutures. As well, the importance of restoring anatomy and tension-free surgical approach in pelvic reconstructive surgery has led to better long-term outcomes and fewer side effects. These principles have been applied when developing the novel BSSVF-M technique. Anticipated challenges of this trial include recruitment, compliance problems and loss to follow up However, the robust methodology will provide evidence on the best surgical approach to correct POP, a common condition among aging women.

PLoS ONEVol. 19(10)
University of British Columbia (CA), University of Alberta (CA), University of Calgary (CA), McGill University (CA), McMaster University (CA)
Pfizer, AbbVie, Michael Smith Health Research BC, Pfizer Canada, Canadian Institutes of Health Research
Industry, innovation and infrastructure
Openalex Percentile: Top 11%
Pelvic floor disorders treatments
2.35
DOIOpen Access PDFOpenAlex
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