Epigenetic aging differentially impacts breast cancer risk by self-reported race
Our study demonstrated that epigenetic age acceleration is associated with BrCa risk, and the association suggests variation by self-reported race. Although our sample size is limited, these results highlight a potential biological mechanism for BrCa risk and identifies a novel research area of BrCa health disparities requiring further inquiry.
Authors
- Fredrick R. Schumacher (ORCID: https://orcid.org/0000-0002-3073-7463)
- Megan E. Miller (ORCID: https://orcid.org/0000-0001-7345-1687)
- Cheryl L. Thompson (ORCID: https://orcid.org/0000-0002-6896-2367)
- Yanning Wu
- Hannah Gilmore
Institutions
- Pennsylvania State University (US)
- University Hospitals of Cleveland (US)
- University School (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1371/journal.pone.0308174
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Division of Cancer Prevention, National Cancer Institute
- Case Comprehensive Cancer Center, Case Western Reserve University
- National Cancer Institute
- Division of Cancer Epidemiology and Genetics, National Cancer Institute