Negative effects on oral motor function after submandibular and parotid botulinum neurotoxin A injections for drooling in children with developmental disabilities

While negative effects on oral motor function were relatively common after four-gland BoNT-A injections, most problems were mild and resolved promptly. No substantial differences to a reference cohort treated with submandibular injections were observed, although further research should establish the generalizability of these findings in a treatment-naive population. Nevertheless, when submandibular injections prove ineffective, clinicians can confidently consider four-gland injections.

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Publication Details

Journal
Developmental Medicine & Child Neurology
Published
2024-10-24
DOI
https://doi.org/10.1111/dmcn.16131
Citations
1
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.37
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article

Negative effects on oral motor function after submandibular and parotid botulinum neurotoxin A injections for drooling in children with developmental disabilities

Corinne P A Delsing, Corrie E. Erasmus, Frank J. A. van den Hoogen, Karen van Hulst et al.
1 citations
Developmental Medicine & Child Neurology
Botulinum Toxin and Related Neurological Disorders
0.37
article

Negative effects on oral motor function after submandibular and parotid botulinum neurotoxin A injections for drooling in children with developmental disabilities

Corinne P A Delsing, Corrie E. Erasmus, Frank J. A. van den Hoogen, Karen van Hulst, Lynn B. Orriëns, Reva M. van Eck
article en
1 citations

Abstract

While negative effects on oral motor function were relatively common after four-gland BoNT-A injections, most problems were mild and resolved promptly. No substantial differences to a reference cohort treated with submandibular injections were observed, although further research should establish the generalizability of these findings in a treatment-naive population. Nevertheless, when submandibular injections prove ineffective, clinicians can confidently consider four-gland injections.

Developmental Medicine & Child NeurologyVol. 67(5)
Radboud University Nijmegen (NL), Radboud University Medical Center (NL), Metropolitan University (BD)
Good health and well-being
Openalex Percentile: Top 34%
Botulinum Toxin and Related Neurological Disorders
0.37
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