Natural progression of basal cell carcinomas in patients awaiting surgical intervention

Basal cell carcinomas (BCCs) are slow-growing keratinocyte tumours. There are few reports in the literature reporting the natural history of untreated BCCs. We evaluated the natural progression of BCCs and patient outcomes while awaiting surgical intervention. Only patients with histologically proven BCCs were included in our analysis. Retrospective data analysis was performed for a sample of 55 patients (in total, 70 lesions). There was a significant correlation between the average growth of BCCs and the time waiting for a procedure, with 20% of patients requiring a more complex procedure than originally planned at the time of booking. The top three most frequently reported symptoms were itching (39.4%), crusting (36.4%) and bleeding (30.3%). We report a positive relationship between BCC growth and the length of time from initial presentation to surgical treatment. Patients with long waits often exhibited more symptoms and required more complex surgical procedures than originally planned, especially for BCCs in the head and neck.

Authors

Institutions

Publication Details

Journal
Clinical and Experimental Dermatology
Published
2024-10-24
DOI
https://doi.org/10.1093/ced/llae460
Citations
1
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
0.39
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Natural progression of basal cell carcinomas in patients awaiting surgical intervention

Andrew Zhao, Helena Wells, Mun Wai Lam, Aaron G. H. Wernham et al.
1 citations
Clinical and Experimental Dermatology
Nonmelanoma Skin Cancer Studies
0.39
article

Natural progression of basal cell carcinomas in patients awaiting surgical intervention

Andrew Zhao, Helena Wells, Mun Wai Lam, Aaron G. H. Wernham, Simon Tso, Heidi Gibbs
article en
1 citations

Abstract

Basal cell carcinomas (BCCs) are slow-growing keratinocyte tumours. There are few reports in the literature reporting the natural history of untreated BCCs. We evaluated the natural progression of BCCs and patient outcomes while awaiting surgical intervention. Only patients with histologically proven BCCs were included in our analysis. Retrospective data analysis was performed for a sample of 55 patients (in total, 70 lesions). There was a significant correlation between the average growth of BCCs and the time waiting for a procedure, with 20% of patients requiring a more complex procedure than originally planned at the time of booking. The top three most frequently reported symptoms were itching (39.4%), crusting (36.4%) and bleeding (30.3%). We report a positive relationship between BCC growth and the length of time from initial presentation to surgical treatment. Patients with long waits often exhibited more symptoms and required more complex surgical procedures than originally planned, especially for BCCs in the head and neck.

Clinical and Experimental DermatologyVol. 50(3)
Chelsea and Westminster Hospital NHS Foundation Trust (GB), Walsall Manor Hospital (GB), Walsall Healthcare NHS Trust (GB), Cardiff University (GB)
Good health and well-being
Openalex Percentile: Top 33%
Nonmelanoma Skin Cancer Studies
0.39
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Natural progression of basal cell carcinomas in patients awaiting surgical intervention — Andrew Zhao, Helena Wells, et al. · Clinical and Experimental Dermatology (2024) | TGRS Research Map | TGRS