New high-numerical-aperture macroscope for low radiation dose tomography at the BMIT Beamlines of the Canadian Light Source

Here we present novel custom-made macroscope designed for high resolution, dose efficient tomographic imaging of small to medium animal models. This instrument was engineered by Optique Peter and has been recently commissioned at Biomedical Imaging and Therapy Beamlines of the Canadian Light Source. Results of the tests will be presented. In addition, we will discuss how different sCMOS cameras, which we use with the macroscope, are integrated in our data acquisition software to provide a unified control interface and to enable rapid preview of tomographic slices. This is essential when working with live animals when quick decisions need to be made during the course of the experiment.