Fundamentals behind the success of nanotechnology in cancer treatment and diagnosis

Nanotechnology is considered one of the most advanced cancer treatment and diagnostic technologies. Due to the numerous benefits of the application of nanoparticles in cancer management, nanotechnology has proven its therapeutic and diagnostic efficiency as an alternative but promising approach against cancer. However, several limitations and challenges continue to pose obstacles to its success. Designing highly precise NPs considering physicochemical factors may lead to successful outcomes in cancer therapy. Besides, the behaviour of NPs with biomolecules in a biological system can be another potential phenomenon of NPs in biomedical applications. Here, we examined the basic aspects, obstacles, and challenges of cancer nanomedicine based on the factors associated with successful clinical outcomes in cancer management to understand this research area comprehensively. Factors crucial in nano-based cancer treatment and diagnosis.