The collagenase-induced osteoarthritis (CIOA) model: Where mechanical damage meets inflammation
By evaluating inflammatory and mechanical factors at different doses and timepoints, our characterization enables a more targeted study design and increases the clinical relevance of future studies involving the CIOA model.
Authors
- Patrick Weber (ORCID: https://orcid.org/0000-0003-3626-000X)
- Kajetana Bevc (ORCID: https://orcid.org/0000-0002-9743-0335)
- Marcy Zenobi‐Wong (ORCID: https://orcid.org/0000-0002-8522-9909)
- Mikko Finnilä (ORCID: https://orcid.org/0000-0002-3348-5759)
- Valentino Bruhin
- Tiejun Zhang (ORCID: https://orcid.org/0000-0002-5224-5822)
- Shipin Zhang (ORCID: https://orcid.org/0000-0001-8421-7108)
- Sami Kauppinen (ORCID: https://orcid.org/0000-0002-4270-2225)
- Tuomas Frondelius
- David Fercher (ORCID: https://orcid.org/0009-0000-8934-9441)
- Gian M. Salzmann (ORCID: https://orcid.org/0000-0001-9892-7100)
- Gonçalo Barreto (ORCID: https://orcid.org/0000-0003-4444-9208)
- Jakob Hax (ORCID: https://orcid.org/0000-0002-7641-052X)
- Maryam Asadikorayem (ORCID: https://orcid.org/0000-0002-3504-4543)
- Lucia Baixauli Marin (ORCID: https://orcid.org/0000-0003-1735-8095)
Institutions
- University of Helsinki (FI)
- University of Zurich (CH)
- Helsinki University Hospital (FI)
- ETH Zurich (CH)
- Schulthess-Klinik (CH)
- Oulu University of Applied Sciences (FI)
- University of Oulu (FI)
Publication Details
- Journal
- Osteoarthritis and Cartilage Open
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1016/j.ocarto.2024.100539
- Citations
- 13
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 6.11
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Eidgenössische Technische Hochschule Zürich
- Oulun Yliopisto
- HORIZON EUROPE Framework Programme