Structural elucidation of 14‐membered ring macrolide antibiotics using electrospray ionization tandem mass spectrometry and density functional theory calculations
Our integrated approach offers a comprehensive understanding of macrolide fragmentation, enhancing structural elucidation and potential applications in drug development. This study advances mass spectrometry analysis of macrolides, contributing to pharmaceutical research by integrating orthogonal annotation methods and fragmentation studies.
Authors
- Fausto Carnevale Neto (ORCID: https://orcid.org/0000-0002-9364-933X)
- Ricardo Vessecchi (ORCID: https://orcid.org/0000-0001-8472-3190)
Institutions
- Universidade de Ribeirão Preto (BR)
- Universidade de São Paulo (BR)
- University of Washington (US)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1002/rcm.9913
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Washington
- Fundação de Amparo à Pesquisa do Estado de São Paulo