Microvascular Inflammation of Kidney Allografts and Clinical Outcomes

Microvascular inflammation in kidney allografts includes distinct phenotypes, with various disease progression and allograft outcomes. Our findings support the clinical use of additional rejection phenotypes to standardize diagnostics for kidney allografts. (Funded by OrganX. ClinicalTrials.gov number, NCT06496269.).

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Publication Details

Journal
New England Journal of Medicine
Published
2024-10-24
DOI
https://doi.org/10.1056/nejmoa2408835
Citations
45
Primary Topic
Renal and Vascular Pathologies
Type
article
Field-Weighted Citation Impact
18.85

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article

Microvascular Inflammation of Kidney Allografts and Clinical Outcomes

Emmanuel Morélon, Brad C. Astor, Vikas R. Dharnidharka, Lionel Couzi et al.
45 citations
New England Journal of Medicine
Renal and Vascular Pathologies
18.85
article

Microvascular Inflammation of Kidney Allografts and Clinical Outcomes

Emmanuel Morélon, Brad C. Astor, Vikas R. Dharnidharka, Lionel Couzi, Mélanie Try, Olivier Aubert, Aurélie Sannier, Rima S. Zahr, Jodi M. Smith, Alaa Alsadi, Bertrand Chauveau, Marc Fila, Valentin Goutaudier, Oriol Bestard, Bradley A. Warady, Edmund Huang, Katherine Twombley, François R. Girardin, Pierre‐Antoine Gourraud, Daniel Yoo, Gillian Divard, Dany Anglicheau, Magali Giral, Julien Hogan, Moglie Le Quintrec, Nassim Kamar, Anne‐Laure Sellier‐Leclerc, Marc Raynaud, Klemens Budde, Arnaud Del Bello, Alexandre Loupy, Marion Rabant, Sophie Brouard, Patricia L. Weng, Richard Danger, Rusan Catar, Raja Dandamudi, Olivia Boyer, Thierry Berney, Marta Sablik, Rouba Garro, Weixiong Zhong, Carmen Lefaucheur, Jean Villard, Jérôme Verine, Christophe Legendre, Burkhard Tönshoff
article en
45 citations

Abstract

Microvascular inflammation in kidney allografts includes distinct phenotypes, with various disease progression and allograft outcomes. Our findings support the clinical use of additional rejection phenotypes to standardize diagnostics for kidney allografts. (Funded by OrganX. ClinicalTrials.gov number, NCT06496269.).

New England Journal of MedicineVol. 392(8)
Université Claude Bernard Lyon 1 (FR), Délégation Paris 5 (FR), Hebron University (PS), Cedars-Sinai Medical Center (US), Hôpital Necker-Enfants Malades (FR), Seattle Children's Hospital (US), Children’s Institute (US), St. Louis Children's Hospital (US), Children's Mercy Hospital (US), University of Wisconsin–Madison (US), Medical University of South Carolina (US), Inserm (FR), University of Washington (US), Université Paris Cité (FR), Saint Louis University Hospital (US), University Hospital Heidelberg (DE), Johnson University (US), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Toulouse (FR), Hôpital Femme Mère Enfant (FR), Sorbonne Paris Cité (FR), Centre Hospitalier Universitaire de Montpellier (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), University Hospital of Geneva (CH), Institut de Transplantation Urologie en Nephrologie (FR), Hôpital Edouard Herriot (FR), Hôpital Robert-Debré (FR), Mattel Children's Hospital (US), Kidney Associates (US), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Hôpital Saint-Louis (FR), Children's Healthcare of Atlanta (US), Wisconsin Division of Public Health (US), Le Bonheur Children's Hospital (US), Geneva College (US), Nantes Université (FR), University of Lausanne (CH)
European Commission, Agence Nationale de la Recherche
Good health and well-being, Zero hunger
Openalex Percentile: Top 0%
Renal and Vascular Pathologies
18.85
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