Release of sputum neutrophil granules is associated with pulmonary function and disease severity in childhood asthma
Sputum MPO and HNL/NGAL levels, which reflect neutrophil activation in airways, were increased in pediatric patients with asthma. Moreover, sputum MPO and HNL/NGAL may serve as appropriate assessment indicators of asthma severity in pediatric patients.
Authors
- Mireu Park (ORCID: https://orcid.org/0000-0003-4342-6143)
- Jong Deok Kim (ORCID: https://orcid.org/0000-0002-4266-5655)
- Myung Hyun Sohn (ORCID: https://orcid.org/0000-0002-2478-487X)
- Min Jung Kim (ORCID: https://orcid.org/0000-0002-5634-9709)
- Kyung Won Kim (ORCID: https://orcid.org/0000-0003-4529-6135)
- Yoon Hee Kim (ORCID: https://orcid.org/0000-0002-2149-8501)
- Soo Yeon Kim (ORCID: https://orcid.org/0000-0003-4965-6193)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Gangnam Severance Hospital (KR)
- Yonsei University Health System (KR)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s12890-024-03340-y
- Citations
- 3
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- National Research Foundation
- Ministry of Trade, Industry and Energy
- Ministry of Science, ICT and Future Planning
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea