Pathophysiological Markers of Acute Respiratory Distress Syndrome Severity Are Correlated With Ventilation-Perfusion Mismatch Measured by Electrical Impedance Tomography
In ARDS patients, unmatched V/Q units are correlated with pathophysiological markers of lung epithelial and endothelial dysfunction, increased lung stress, and lung edema. Unmatched V/Q units could represent a comprehensive marker of ARDS severity, reflecting the complex organ pathophysiology and reinforcing their prognostic significance.
Authors
- Valentina Vaira (ORCID: https://orcid.org/0000-0003-4416-6216)
- Marco Leali (ORCID: https://orcid.org/0000-0001-8792-991X)
- Mauro Panigada (ORCID: https://orcid.org/0000-0003-4841-9794)
- Fabiana Madotto (ORCID: https://orcid.org/0000-0002-8829-9160)
- Tommaso Mauri (ORCID: https://orcid.org/0000-0002-2709-8162)
- Nadia Mansour (ORCID: https://orcid.org/0000-0001-7690-7096)
- Giacomo Grasselli (ORCID: https://orcid.org/0000-0002-1735-1400)
- Elena Spinelli (ORCID: https://orcid.org/0000-0002-8061-252X)
- Joaquin Perez
- Valentina Chiavieri
- Lorenzo Rosso (ORCID: https://orcid.org/0000-0002-9809-7140)
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1097/ccm.0000000000006458
- Citations
- 7
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.93