Treatment optimisation for blood pressure with single-pill combinations in India (TOPSPIN) – Protocol design and baseline characteristics
The TOPSPIN trial is the first randomised evaluation of commonly used BP-lowering combination therapies in a South Asian population. The results have potentially significant implications for choosing first-line antihypertensive agents among Indians and the South Asian diaspora.
Authors
- Goldaa Mahajan
- Edmin Christa
- Vinod K. Abichandani
- Amit Malviya (ORCID: https://orcid.org/0000-0002-3326-6177)
- Dimple Kondal (ORCID: https://orcid.org/0000-0002-1417-9510)
- Ambalam M. Chandrasekaran (ORCID: https://orcid.org/0000-0002-6924-7162)
- Shantanu Sengupta (ORCID: https://orcid.org/0000-0001-8461-0735)
- Dorairaj Prabhakaran (ORCID: https://orcid.org/0000-0002-3172-834X)
- Satish Gurunathrao Patil (ORCID: https://orcid.org/0000-0001-8502-0884)
- Vipul Chavda
- Kavita Singh (ORCID: https://orcid.org/0000-0003-4330-666X)
- Somnath Mukherjee (ORCID: https://orcid.org/0000-0001-5447-4496)
- Kiran Aithal (ORCID: https://orcid.org/0000-0001-7426-404X)
- Bhupinder Singh (ORCID: https://orcid.org/0009-0006-4779-2553)
- Ambuj Roy (ORCID: https://orcid.org/0000-0001-6418-4388)
- Victoria Cornelius (ORCID: https://orcid.org/0000-0002-0080-1065)
- Gaia Kiru
- Mallika Khanna
- Aman Khanna (ORCID: https://orcid.org/0000-0001-7212-3673)
- António Lobo (ORCID: https://orcid.org/0000-0002-9098-655X)
- Neil Bardoloi (ORCID: https://orcid.org/0000-0002-5997-063X)
- Animesh Mishra (ORCID: https://orcid.org/0000-0002-7237-7961)
- Sunil Kumar (ORCID: https://orcid.org/0000-0001-9957-5661)
- Bishav Mohan
- Bal Kishan Gupta (ORCID: https://orcid.org/0000-0002-3222-0011)
- D Shailendra
- Neil Poulter
- Balsubramaiam Yellapantula
- Hyndavi Salwa (ORCID: https://orcid.org/0000-0002-6916-1107)
Institutions
- Nagpur Institute of Technology (IN)
- Heidelberg University (DE)
- North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (IN)
- Sardar Patel Medical College (IN)
- CARE Hospitals (IN)
- Mediciti Institute of Medical Sciences (IN)
- Sri Dharmasthala Manjunatheshwara College of Dental Sciences & Hospital (IN)
- Mahatma Gandhi Dental College & Hospital (IN)
- Indian Institute of Information Technology Vadodara (IN)
- Rajendra Hospital (IN)
- Centre for Chronic Disease Control (IN)
- Datta Meghe Institute of Higher Education and Research (IN)
- Public Works Department Buildings and Roads (IN)
- Imperial College London (GB)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- International Journal of Cardiology Cardiovascular Risk and Prevention
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1016/j.ijcrp.2024.200346
- Citations
- 6
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.41
Funders
- Imperial College London
- Servier