Distinct roles of two homologous kinesins in mammalian motile cilia

How do the two kinesin-9 members Kif6 and Kif9 function in mammalian cilia? Ou and colleagues discuss new work from Fang et al. (https://doi.org/10.1083/jcb.202312060) showing that Kif6 is an active motor while Kif9 serves as a stationary regulator, both of which are essential for cilia motility.

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Publication Details

Journal
The Journal of Cell Biology
Published
2024-10-24
DOI
https://doi.org/10.1083/jcb.202409214
Citations
1
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
0.55
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article

Distinct roles of two homologous kinesins in mammalian motile cilia

Kaiming Xu, Guangshuo Ou, Ming Li
1 citations
The Journal of Cell Biology
Genetic and Kidney Cyst Diseases
0.55
article

Distinct roles of two homologous kinesins in mammalian motile cilia

Kaiming Xu, Guangshuo Ou, Ming Li
article en
1 citations

Abstract

How do the two kinesin-9 members Kif6 and Kif9 function in mammalian cilia? Ou and colleagues discuss new work from Fang et al. (https://doi.org/10.1083/jcb.202312060) showing that Kif6 is an active motor while Kif9 serves as a stationary regulator, both of which are essential for cilia motility.

The Journal of Cell BiologyVol. 223(11)
McGovern Institute for Brain Research (US), Center for Life Sciences (CN), Tsinghua University (CN)
Openalex Percentile: Top 25%
Genetic and Kidney Cyst Diseases
0.55
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