Neutrophil extracellular traps as immunofibrotic mediators in RA-ILD; pilot evaluation of the nintedanib therapy
The findings propose an interplay between circulating NETs and HPFs, establishing the immunofibrotic aspects of RA-ILD. They also support the effectiveness of nintedanib in reducing key pathological processes of the disease. Further research is needed to fully understand these mechanisms and optimize treatment strategies for RA-ILD.
Authors
- Akrivi Chrysanthopoulou (ORCID: https://orcid.org/0000-0002-0325-6146)
- Aliki I. Venetsanopoulou (ORCID: https://orcid.org/0000-0003-4280-9193)
- Eleni Papagianni (ORCID: https://orcid.org/0000-0001-7457-9201)
- Nikolaos Koletsos (ORCID: https://orcid.org/0000-0001-6976-2802)
- Maria Ntinopoulou (ORCID: https://orcid.org/0009-0001-7558-5133)
- Paraskevi V. Voulgari
Institutions
- University of Ioannina (GR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1480594
- Citations
- 9
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 3.77