Magnetic protein aggregates generated by supramolecular assembly of ferritin cages - a modular strategy for the immobilization of enzymes
This study presents a modular strategy for the <i>in vivo</i> production of MPAs as scaffold for enzyme immobilization. The approach eliminates the need for traditional, expensive carriers and simplifies the purification process by leveraging the insoluble nature and the magnetic properties of the aggregates, opening up the potential for novel, streamlined applications in biocatalysis.
Authors
- Dietrich Kohlheyer (ORCID: https://orcid.org/0000-0001-6215-1857)
- Karl‐Erich Jaeger (ORCID: https://orcid.org/0000-0002-6036-0708)
- Ulrich Krauß (ORCID: https://orcid.org/0000-0003-2219-7388)
- Bastian Wollenhaupt (ORCID: https://orcid.org/0000-0002-8144-6930)
- Gizem Ölçücü (ORCID: https://orcid.org/0000-0001-5126-4530)
Institutions
- Forschungszentrum Jülich (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Bayreuth (DE)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-10-23
- DOI
- https://doi.org/10.3389/fbioe.2024.1478198
- Citations
- 1
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Forschungszentrum Jülich
- European Regional Development Fund