Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study
Based on this 1:4 individual-matched case‒control study, the SNP rs56163822 in the <i>NR1H4</i> gene may be linked to the susceptibility to AT-DILI in Chinese patients receiving anti-TB treatment. Further studies in larger varied populations are needed to validate our findings.
Authors
- Lihuan Lu
- Jing-Ru C. Cheng (ORCID: https://orcid.org/0000-0002-2281-0288)
- Hongqiu Pan (ORCID: https://orcid.org/0000-0002-7091-3230)
- Xiaoyan Xu (ORCID: https://orcid.org/0000-0003-0894-1895)
- Shaowen Tang (ORCID: https://orcid.org/0000-0001-5879-8594)
- Honggang Yi
- Ruina Chen
- Meiling Zhang (ORCID: https://orcid.org/0000-0002-0996-9702)
- Xiaomin He (ORCID: https://orcid.org/0000-0002-6079-1014)
Institutions
- Jiangsu University (CN)
- Taixing People's Hospital (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Changshu No.1 People's Hospital (CN)
- Xian Yang Central Hospital (CN)
- Gansu Provincial Center for Disease Control and Prevention (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-10-23
- DOI
- https://doi.org/10.3389/fgene.2024.1428319
- Citations
- 1
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China