Association of triglyceride-glucose index and its combination with obesity indicators in predicting the risk of aortic aneurysm and dissection
The present study, based on a large prospective cohort design, showed that higher TyG index and its combination with obesity indices were significantly associated with the risk of AAD. Moreover, AFT models further showed that elevation of these indicators significantly advanced the onset of AAD. In addition, RCS analyses demonstrated a linear association between these indicators and the risk of AAD, and the TyG-WC showed higher predictive ability for AAD. These findings emphasize the potential application of the TyG index and its combination with obesity indicators in the early identification of AAD.
Authors
- Wenke Cheng
- Wen‐Chung Yu (ORCID: https://orcid.org/0000-0003-3899-0022)
- Xiaoling Wang (ORCID: https://orcid.org/0000-0001-9290-7926)
- Zhongyan Du
Institutions
- Zhejiang Chinese Medical University (CN)
- Leipzig University (DE)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-10-23
- DOI
- https://doi.org/10.3389/fnut.2024.1454880
- Citations
- 9
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 3.77
Funders
- Wellcome Trust
- Northwest Regional Development Agency
- China Scholarship Council
- Medical Research Council
- Natural Science Foundation of Zhejiang Province