The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Concurrent omeprazole and clopidogrel administration was associated with altered pharmacokinetics on day 10, but no difference in pharmacodynamics between the 2 treatment groups. The short-term use of clopidogrel and omeprazole does not seem to alter platelet function significantly.

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Publication Details

Journal
Journal of Veterinary Internal Medicine
Published
2024-10-23
DOI
https://doi.org/10.1111/jvim.17198
Citations
3
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
1.21

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article

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Céline Plante, Jillian M. Haines, Michael H. Court, O. Lynne Nelson et al.
3 citations
Journal of Veterinary Internal Medicine
Antiplatelet Therapy and Cardiovascular Diseases
1.21
article

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Céline Plante, Jillian M. Haines, Michael H. Court, O. Lynne Nelson, Pamela M. Lee, Stephanie E. Martinez
article en
3 citations

Abstract

Concurrent omeprazole and clopidogrel administration was associated with altered pharmacokinetics on day 10, but no difference in pharmacodynamics between the 2 treatment groups. The short-term use of clopidogrel and omeprazole does not seem to alter platelet function significantly.

Journal of Veterinary Internal MedicineVol. 38(6)
Kansas State University (US), Englewood Hospital and Medical Center (US), Cegep de Saint Hyacinthe (CA), Université de Montréal (CA), Washington State University (US)
Washington State University
Good health and well-being
Openalex Percentile: Top 18%
Antiplatelet Therapy and Cardiovascular Diseases
1.21
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