The combination of CDX2 expression status and tumor-infiltrating lymphocyte density as a prognostic factor in adjuvant FOLFOX-treated patients with stage III colorectal cancers
Altogether, a high density of CD8 iTILs did not make a difference in the survival of patients with CRC with CDX2 loss. The combination of CDX2 expression and intraepithelial CD8 TIL density was an independent prognostic marker in adjuvant chemotherapy-treated patients with stage III CRC.
Authors
- Lingyan Jin
- Hye Eun Park (ORCID: https://orcid.org/0000-0003-1048-2827)
- Hye‐Yeong Jin
- Nam-Yun Cho
- Gyeong Hoon Kang (ORCID: https://orcid.org/0000-0003-2380-6675)
- Seung Yeon Yoo (ORCID: https://orcid.org/0000-0002-7226-4238)
- Jung Ho Kim (ORCID: https://orcid.org/0000-0002-5033-3482)
- Ji-Ae Lee
- Jeong Mo Bae
Institutions
- Seoul National University (KR)
- Seoul National University Bundang Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
Publication Details
- Journal
- Journal of Pathology and Translational Medicine
- Published
- 2024-10-23
- DOI
- https://doi.org/10.4132/jptm.2024.09.26
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea