Zibibbo Grape Seeds’ Polyphenolic Profile: Effects on Bone Turnover and Metabolism
Zibibbo grape seeds are rich in phenolic compounds, especially flavonoids with strong antioxidant and free radical scavenging properties. ZSE demonstrated beneficial effects on bone metabolism and osteoblast proliferation, suggesting potential for counteracting osteodegenerative conditions like osteoporosis. If confirmed through further studies, Zibibbo grape seed phenolic compounds could serve as an adjunctive therapy for osteoporosis, helping to slow aging and bone degeneration.
Authors
- Rosario Mare (ORCID: https://orcid.org/0000-0003-0881-4036)
- Antonio Cardamone (ORCID: https://orcid.org/0000-0002-9091-1806)
- Tiziana Montalcini (ORCID: https://orcid.org/0000-0001-7048-5830)
- Anna Rita Coppoletta
- Luca Tirinato (ORCID: https://orcid.org/0000-0001-9826-2129)
- Samantha Maurotti (ORCID: https://orcid.org/0000-0001-7644-1337)
- Arturo Pujia
- Vincenzo Musolino (ORCID: https://orcid.org/0000-0003-4177-534X)
- Mariagiovanna Settino
- Simona Greco
Institutions
- Magna Graecia University (IT)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-10-23
- DOI
- https://doi.org/10.3390/ph17111418
- Citations
- 5
- Primary Topic
- African Botany and Ecology Studies
- Type
- article
- Field-Weighted Citation Impact
- 10.35