Phthalate exposure induces cell death and ferroptosis in neonatal microglial cells
This study indicates that neonatal exposure to DEHP may be linked to neurodevelopmental impairment via inflammation-related cell death and ferroptosis. The prevalence of DEHP in NICU medical devices raises concerns about potential neurodevelopmental deficits, including disorders like autism and mental retardation. These findings highlight the urgency of addressing DEHP exposure in neonatal care.
Authors
- Hayrünnisa Bolay (ORCID: https://orcid.org/0000-0002-3357-7733)
- Elif Topa (ORCID: https://orcid.org/0000-0001-5140-1451)
- Hasan Hüseyin Kazan (ORCID: https://orcid.org/0000-0001-7936-8606)
- Zübeyir Elmazoğlu (ORCID: https://orcid.org/0000-0003-4527-8834)
- Arzu Aral (ORCID: https://orcid.org/0000-0002-7300-1624)
- Elif Keleş (ORCID: https://orcid.org/0000-0001-8103-797X)
- Mehmet Ali Ergün (ORCID: https://orcid.org/0000-0001-9696-0433)
Institutions
- Northwestern University (US)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2024-10-18
- DOI
- https://doi.org/10.55730/1300-0144.5889
- Citations
- 6
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 1.89