Correlation of T Regulatory Cells, Cytotoxic T-lymphocyte-associated Antigen 4, and Transforming Growth Factor-β1 with Treatment Response in Patients with Chronic Myeloid Leukemia Receiving Dasatinib Therapy
The study concluded that dasatinib treatment improved response in CML patients with decreased Treg cells. Dasatinib reduces Treg-mediated immunological suppression, reducing CTLA-4 and TGF-β1 levels.
Authors
- Anurag Kumar Singh (ORCID: https://orcid.org/0000-0003-0818-0993)
- Akanksha Singh (ORCID: https://orcid.org/0000-0001-7206-3965)
- Wahid Ali (ORCID: https://orcid.org/0000-0002-0474-6200)
- Rashmi Kushwaha (ORCID: https://orcid.org/0000-0002-0581-2177)
- Uma Shankar Singh (ORCID: https://orcid.org/0000-0002-9748-9484)
- Shailendra Prasad Verma
Institutions
- King George's Medical University (IN)
Publication Details
- Journal
- Annals of African Medicine
- Published
- 2024-10-23
- DOI
- https://doi.org/10.4103/aam.aam_5_24
- Citations
- 1
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.45