Promotion of Epithelial Healing in Oral Mucositis by hESC-derived Mesenchymal Stem Cells <i>via</i> the PI3K/AKT Pathway
These findings suggest that hESC-MSCs promoted OM wound healing by stimulating the proliferation of epithelial cells and inhibiting their apoptosis in rat models. Furthermore, hESC-MSCs might mediate the PI3K/AKT pathway to modulate apoptosis/proliferation injured by LPS or 5-FU in HaCaT cells.
Authors
- Kejia Lv
- Hua Yao (ORCID: https://orcid.org/0000-0001-6247-0559)
- Bicong Gao
- Weijia Ye
- Tianchi Chen
- Chenlu Shen
- Chaowei Wang
Institutions
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Current Stem Cell Research & Therapy
- Published
- 2024-10-23
- DOI
- https://doi.org/10.2174/011574888x338333241010104024
- Citations
- 1
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.42