Multiple Machine Learning Models, Molecular Subtyping and Singlecell Analysis Identify PANoptosis-related Core Genes and their Association with Subtypes in Crohn’s Disease
This study is the first to construct a PANoptosis signature with excellent efficacy in recognising CD. PANoptosis may mediate the process of CD through inflammatory and immune mechanisms, such as NF- kappaB, MAPK and leukocyte migration.
Authors
- Rong‐Quan He (ORCID: https://orcid.org/0000-0002-7752-2080)
- Zhi‐Guang Huang (ORCID: https://orcid.org/0000-0003-4457-9491)
- Gang Chen (ORCID: https://orcid.org/0000-0002-4864-1451)
- Wan-Ying Huang (ORCID: https://orcid.org/0000-0002-8314-5963)
- Juan He (ORCID: https://orcid.org/0000-0002-6485-1336)
- Yi Chen (ORCID: https://orcid.org/0000-0003-0236-7263)
- Hui Li
- Rui Song (ORCID: https://orcid.org/0009-0004-0306-1455)
- Lu Zhang (ORCID: https://orcid.org/0009-0004-0981-995X)
- Jiawei Zhang (ORCID: https://orcid.org/0009-0002-9588-7339)
Institutions
- Guangxi Medical University (CN)
- Guigang City People's Hospital (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2024-10-23
- DOI
- https://doi.org/10.2174/0109298673330894241008060309
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.68