E2F-1–Akt1 Interaction as Precursor to Cisplatin-induced Apoptosis in Triple-negative Breast Cancer Cells

Our findings suggest a potential interaction between E2F-1 and Akt1, which in turn could be the precursor for the cisplatin-induced apoptosis in TNBC cells. Further studies are needed to determine whether this interaction occurs directly or via an intermediate protein.

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Publication Details

Journal
Oman Medical Journal
Published
2024-10-23
DOI
https://doi.org/10.5001/omj.2025.41
Primary Topic
Cancer-related Molecular Pathways
Type
article
Field-Weighted Citation Impact
0.00

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article

E2F-1–Akt1 Interaction as Precursor to Cisplatin-induced Apoptosis in Triple-negative Breast Cancer Cells

Shadia Al-Bahlani, Buthaina Al-Dhahli, Samiya Al‐Jaaidi, Asma Al Sibani et al.
1 links
Oman Medical Journal
Cancer-related Molecular Pathways
article

E2F-1–Akt1 Interaction as Precursor to Cisplatin-induced Apoptosis in Triple-negative Breast Cancer Cells

Shadia Al-Bahlani, Buthaina Al-Dhahli, Samiya Al‐Jaaidi, Asma Al Sibani, Thraia Al Harthi, Hajar Al Ghafri
article en

Abstract

Our findings suggest a potential interaction between E2F-1 and Akt1, which in turn could be the precursor for the cisplatin-induced apoptosis in TNBC cells. Further studies are needed to determine whether this interaction occurs directly or via an intermediate protein.

Oman Medical JournalVol. 40(1)
Sultan Qaboos University Hospital (OM), Sultan Qaboos University (OM)
Sultan Qaboos University
Good health and well-being
Openalex Percentile: Top 67%
Cancer-related Molecular Pathways
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