Active CNS delivery of oxycodone in healthy and endotoxemic pigs
This study enhances our understanding of oxycodone pharmacokinetics and CNS drug delivery in both healthy and inflamed conditions, providing crucial insights for translating these findings to clinical settings.
Authors
- Irena Loryan (ORCID: https://orcid.org/0000-0002-1557-4416)
- Jai Kumar Mahajan (ORCID: https://orcid.org/0000-0003-0006-2028)
- Stina Syvänen (ORCID: https://orcid.org/0000-0002-8196-4041)
- Miklós Lipcsey (ORCID: https://orcid.org/0000-0002-1976-4129)
- Frida Bällgren
- Margareta Hammarlund‐Udenaes (ORCID: https://orcid.org/0000-0002-9181-1321)
- Tilda Bergfast
- Aghavni Ginosyan
Institutions
- Uppsala University (SE)
- Uppsala University Hospital (SE)
- Abertay University (GB)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2024-10-23
- DOI
- https://doi.org/10.1186/s12987-024-00583-z
- Citations
- 3
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.33
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- Vetenskapsrådet
- Uppsala Universitet
- Innovative Medicines Initiative