Cardiometabolic Risk Assessment in Transgender Individuals—Differential Effect of Sex Hormones and Sex Chromosomes
The results are consistent with increased cardiometabolic risk in transgender men, while transgender women show beneficial changes early during gender-affirming hormone therapy. Sex chromosomes have fewer intrinsic effects. XY individuals and transgender men display an increased apparent diabetes risk. Further research on cardiometabolic risk is needed for transgender individuals.
Authors
- Margery A. Connelly (ORCID: https://orcid.org/0000-0002-3917-592X)
- Anna Wiik
- Daniel P. Andersson (ORCID: https://orcid.org/0000-0003-4655-4837)
- Linnea Lindberg
- Stefan Arver (ORCID: https://orcid.org/0000-0002-2925-355X)
- Uwe J.F. Tietge (ORCID: https://orcid.org/0000-0001-9469-7651)
- Lei Yu (ORCID: https://orcid.org/0000-0001-7246-8305)
- Thomas Gustafsson (ORCID: https://orcid.org/0000-0002-1559-4206)
Institutions
- Karolinska University Hospital (SE)
- LabCorp (United States) (US)
- Karolinska Institutet (SE)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-10-23
- DOI
- https://doi.org/10.1210/clinem/dgae745
- Citations
- 1
- Primary Topic
- LGBTQ Health, Identity, and Policy
- Type
- article
- Field-Weighted Citation Impact
- 0.64
Funders
- Fredrik och Ingrid Thurings Stiftelse
- Stockholms Läns Landsting
- Stockholm läns landsting
- Center for Innovative Medicine