Interleukin‐6 transcripts up‐regulation in lymph nodes from unicentric and multicentric Castleman disease
Our findings suggest that nodal IL-6 expression seems to be significantly upregulated in HHV8+ MCD, but a trend toward increased nodal IL-6 expression was noticed also in UCD and iMCD-not otherwise specified. CD31+ endothelial cells probably represent one of the major sources of IL-6 production in the nodal microenvironment.
Authors
- Sara Fraticelli (ORCID: https://orcid.org/0000-0002-7932-8185)
- Marco Paulli (ORCID: https://orcid.org/0000-0003-2454-5980)
- Caterina Cristinelli (ORCID: https://orcid.org/0000-0002-5757-3569)
- Luca Arcaini (ORCID: https://orcid.org/0000-0002-9504-991X)
- Erica Travaglino (ORCID: https://orcid.org/0000-0003-4985-339X)
- Gaia Morello (ORCID: https://orcid.org/0000-0003-3400-8732)
- Paolo Libretti
- Marco Lucioni (ORCID: https://orcid.org/0000-0002-6244-3646)
- Francesca Antoci
- Giuseppe Neri (ORCID: https://orcid.org/0000-0002-8675-1897)
- Claudio Tripodo (ORCID: https://orcid.org/0000-0002-0821-6231)
- Marcello Gambacorta
- Marco Minetto
Institutions
- University of Pavia (IT)
- IFOM (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Palermo (IT)
Publication Details
- Journal
- eJHaem
- Published
- 2024-10-23
- DOI
- https://doi.org/10.1002/jha2.1034
- Citations
- 1
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.28