MANIFESTAÇÕES ORAIS DAS LEUCEMIAS EM PACIENTES PEDIÁTRICOS

Leukemias can be described as blood dyscrasias resulting from the disordered multiplication of hematopoietic tissue cells. The manifestations of the disease occur systemically and have a major impact on the oral cavity, with repercussions in response to the disease itself and to elective treatment, whether surgical, chemo- or radiotherapy. The objective of this study is to discuss the oral alterations of greatest clinical value in pediatric patients, discussing the role of the dentist in the diagnosis and treatment of these manifestations. The study was carried out from the perspective of an integrative bibliographic review, following the previously established inclusion and exclusion criteria. The results emphasize the correlation between oral health and the integrity of all systems, demonstrating that the most prevalent alterations are oral mucositis, gingival enlargement followed by spontaneous bleeding and petechiae, opportunistic infections, cavities, xerostomia and hyposalivation. It is therefore concluded that there is a need for the dentist to evaluate and monitor the treatment process of pediatric patients with leukemia who are the target of antineoplastic therapy.